Symbol
Name
ID

Erbb2
erb-b2 receptor tyrosine kinase 2
MGI:95410

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

nervous system phenotype

kinked neural tube

abnormal muscle spindle morphology

decreased muscle spindle number

abnormal enteric ganglia morphology

abnormal enteric neuron morphology

abnormal sympathetic ganglion morphology

abnormal paravertebral ganglion morphology

abnormal oligodendrocyte morphology

decreased Schwann cell precursor number

decreased Schwann cell number

abnormal motor neuron innervation pattern

abnormal sensory neuron innervation pattern

abnormal myelin sheath morphology

decreased neuronal precursor cell number

abnormal cranial ganglia morphology

abnormal cochlear ganglion morphology

abnormal geniculate ganglion morphology

abnormal petrosal ganglion morphology

abnormal trigeminal ganglion morphology

small superior vagus ganglion

abnormal cranial nerve morphology

abnormal glossopharyngeal nerve morphology

abnormal hypoglossal nerve morphology

abnormal trigeminal nerve morphology

abnormal vagus nerve morphology

abnormal dorsal root ganglion morphology

abnormal dorsal spinal root morphology

abnormal sciatic nerve morphology

abnormal ventral spinal root morphology

abnormal myelination

demyelination

abnormal excitatory postsynaptic potential

Availability

Mouse Genotype

Erbb2^l11Jus8/Erbb2^l11Jus8

Erbb2^tm1Cbm/Erbb2^tm1Cbm

Erbb2^tm1Gne/Erbb2^tm1Gne

Erbb2^tm1Haus/Erbb2^tm1Haus

Erbb2^tm1Mul/Erbb2^tm1Mul

Erbb2^tm1Vrtn/Erbb2^tm1Vrtn

Erbb2^tm2Mul/Erbb2^tm2Mul

Erbb2^{tm8.1(Erbb2)Mul}/Erbb2^{tm8.1(Erbb2)Mul}

Erbb2^tm1Cbm/Erbb2⁺

Erbb2^tm1Cbm/Erbb2^tm2.1Cbm

Erbb2^{tm8.1(Erbb2)Mul}/Erbb2⁺

Erbb2^tm1Klee/Erbb2^tm1Klee
Tg(Nes-cre)1Atp/0 (conditional)

Egr2^tm2(cre)Pch/Egr2⁺
Erbb2^tm2Cbm/Erbb2^tm2Cbm (conditional)

Egr2^tm2(cre)Pch/Egr2⁺
Erbb2^tm1Cbm/Erbb2^tm2Cbm (conditional)

Erbb2^tm1Haus/Erbb2^tm1Klee
Myf5^tm3(cre)Sor/Myf5⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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